The Growing Danger of Kidney Issues- A Silent Global Epidemic

Doctor, I don’t feel sick, but my legs are swelling, and I feel tired all the time.”

Imagine an organ that work persistently- filtering 50 gallons of Blood per day, removing waste material, regulating blood pressure, and balancing vital minerals. If this organ slowly failing, without any symptoms, until it reaches a critical stage. This is the silent danger of kidney issues. Unlike heart attack or stroke, kidney disease doesn’t reveal immediate warning signs. It progresses silently, often going undetected until 90% of kidney function is lost. By then, the damage is irreversible, leading to dialysis, organ transplantation or death.

Chronic kidney disease (CKD) affects nearly 10- 17% of the India’s population, with End-Stage Renal Disease (ESRD) is 150- 200 per 10 lakhs causes increasing at an alarming rate.

Chronic kidney disease (CKD) rank as the 8th leading cause of death and is estimated to affects more than 850 million people worldwide and become the 5th largest cause of year of life lost by 2040. This CKD epidemic has caused a major economic strain not only in developing countries but also in low- income and middle – income countries.

  • About 1 in 3 adults with diabetes and 1 in 5 adults with high blood pressure may have kidney disease.
  • Diabetes is the most common cause of kidney disease, diabetes and hypertension contribute to 2 to 3 new cases of kidney failure.
  • Black / African American people have 4 times the incidence of kidney failure (ESKD) as white person.
  • About 35.5 million U.S Adult are estimated to have kidney disease -that more than 1 in 7(14%).
Prevalence of kidney disease –
  • Chronic kidney disease (CKD) affects nearly 10- 17% of the India’s population, with End-Stage Renal Disease (ESRD) is approximately 150- 200 per million population.
  • Mortality Trends- Between 2001-2003 and 2010-13, there was 38% increase in death attributable of kidney failure in India.
  • Dialysis outcomes Recent studies finds 7 out of 10 dialysis patients in india survive beyond 6 months, with rural patients experiencing a 32% higher mortality rate compared to urban patients.
  • Transplantation GapIn 2022, over 200, 000 patients required kidney transplants, but only about 7,500(3.4%) were performed, highlighting a significant organ shortage.
Chronic kidney disease (CKD)becoming an increasingly concerning health issues in India.

The review, which analyzed community – based, representative evidence gathered between 2011 and 2023, indicate significant rise in CKD cases among Indians aged 15 years and above.

  • CKD now impact 13.24% of India, with prevalence increasing from 11.12% between 2011 and 2017 to 16.38% between 2018 and 2023 among individuals aged between 15 years and above.
  • The Meta-analysis, published in Nephrology journal, reveals that CKD is more prevalent in rural areas (15.34%) compared to urban regions (10.65%), and in men (14.80%) compared to women (13.51%). The highest prevalence was found in southern india, where it reached 14.78%

Kidney diseases are becoming a significant health concern in India due to multiple factors such as lifestyle changes, increasing diabetes and hypertension rates, lack of awareness, and limited access to healthcare in rural areas. Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) are on the rise, posing a major burden on the healthcare system.

Key Factors Contributing to Rising Kidney Issues in India
1. Diabetes and Hypertension-

India is the diabetes capital of the world, with over 77 million diabetics (as of 2023). Diabetes and high blood pressure are the leading causes of kidney failure.

2. Unhealthy Lifestyle Choices-

Lack of Physical activity, unhealthy diets and Excessive stress contribute to kidney issues.

3. Delayed Diagnosis and Lack of Awareness-
  • Many people are unaware of kidney disease until it reaches an advanced stage, making treatment difficult.
  • Routine kidney function tests are not common among the general population.
4. Pollution and Contaminated Water-
  • Heavy metal contamination (such as Arsenic and Fluoride) in groundwater in many parts of India affects kidney health.
  • Pesticide use in agriculture has also been linked to kidney disorders.
5. Overuse of Painkillers and Unregulated Medications-
  • Self-medication, especially excessive consumption of NSAIDs (painkillers like ibuprofen), damages kidneys over time.
  • Traditional and herbal medicines without medical supervision can also cause kidney toxicity.
6. Limited Access to Dialysis and Transplant Facilities-
  • India faces a shortage of Dialysis centers and Trained Nephrologists.
  • Kidney transplants are expensive, and there is a huge gap between demand and availability of donor organs.
7. Genetics

Family history can increase the risk of kidney disease.

Early Warning Signs: Recognizing the Silent Symptoms-

Since kidney disease progresses silently, early detection is key. Common symptoms include:

  • Swelling (Edema): Retention of fluid in the legs, face, or hands.
  • Persistent Fatigue: Caused by toxin buildup and Anemia.
  • Changes in Urination: Presence of blood in urine, or reduced urine output, Foamy urine.
  • High Blood Pressure: Unmanaged High Blood Pressure is both a cause and consequence of Kidney Disease.
  • Loss of Appetite and Nausea:Due to Accumulation of toxin in the Blood.

Early diagnosis through urine tests, blood creatinine levels, and imaging techniques can prevent disease progression.

Advances in Kidney Disease Management-
  • Early Screening and AI-Based Diagnostics

AI-powered screening tools can predict CKD risk years in advance, allowing for early intervention.

Wearable technology and smart urine analysis devices are improving real-time kidney health monitoring.

  • Medical and Pharmacological Innovations

-SGLT2 Inhibitors (e.g., Dapagliflozin, Empagliflozin): Proven to slow CKD progression, even in Non-Diabetic Patients.

-New Anti-Fibrotic Drugs: Designed to reduce kidney scarring and preserve function.

  • Alternative Treatments: Regenerative Medicine and Bioengineering

-Stem cell therapies are being developed to repair damaged kidney tissue.

-Scientists are working on 3D-printed bioengineered kidneys as a potential alternative to organ transplants.

  • Improved Dialysis and Transplantation Methods

-Portable and home-based dialysis machines are making treatment more accessible.

-Advances in immunosuppressive drugs have significantly improved kidney transplant survival rates.

Preventive Measures: Steps to Protect Kidney Health-
  • Regular Health Check-ups: Early detection through blood and urine tests can prevent disease progression.
  • Healthy Diet & Hydration: Increase fruits, vegetables, and reduce salt intake.
  • Exercise & Weight Management: A healthy weight helps regulate blood sugar and blood pressure.
  • Medication Awareness: Avoid self-medication and consult a doctor before using painkillers or herbal medicines.
  • Environmental Protection: Clean drinking water and protective measures for outdoor workers can reduce risk.
Government Initiatives & Solutions-
  • National Dialysis Program: Provides free dialysis services at government hospitals.
  • Ayushman Bharat Scheme: Covers kidney disease treatment costs.
  • Organ Donation Awareness Programs: Encourages kidney transplants to address the organ shortage.
Impact of communication in raising awareness –
  • Mass communication plays a crucial role in spreading awareness about kidney disease, which often progress silently.
  • Television, Newspaper, Radio and Digital platform actively educate people about –
    • Importance of early detection.
    • Risk factors of kidney diseases.
    • Preventives measures to maintain kidney health.
  • Government and health care organizations must launch awareness campaigns focusing on-

-Risk of self-medication and overused of painkiller.

-Regular kidney screening.

– Adaptive healthy lifestyle choices.

  • Workplace, educational institutions and community centre should actively participate in awareness program to help peoples make informed health decision.

Kidney health is not just a medical issue—it’s a life-or-death wake-up call. Let’s dive in and uncover the truth about the silent epidemic threatening millions.

Conclusion: A Call for Awareness & Action

Kidney disease is a silent killer, often diagnosed too late. With India’s growing burden of Diabetes, Hypertension, and Environmental risks, Proactive steps are needed. By making small but significant lifestyle changes, staying informed and undergoing regular health checkup, we can protect our kidneys and lead to healthier lives.

However, prevention is not just an individual responsibility – it requires collective action. Government, medical profession, Media organizations, and individuals must work together to raise awareness, ensure early diagnosis, and provide accessible healthcare solutions.

Taking care of your Kidneys today ensures a Healthier Tomorrow!

References-

1.Glassock R. J., WarnocD. G., Delanaye P. The global burden of chronic kidney disease: estimates, variability and pitfalls. Nature Reviews Nephrology . 2017;13(2):104–114. doi: 10.1038/nrneph.2016.163. [DOI] [PubMed] [Google Scholar]

2.Mills K. T., Xu Y., Zhang W., et al. A systematic analysis of worldwide population-based data on the global burden of chronic kidney disease in 2010. Kidney International . 2015;88(5):950–957. doi: 10.1038/ki.2015.230. [DOI] [PMC free article] [PubMed] [Google Scholar]

3.de Boer I. H., Khunti K., Sadusky T., et al. Diabetes management in chronic kidney disease: a consensus report by the American diabetes association (ADA) and kidney disease: improving global outcomes (KDIGO) Kidney International . 2022;102(5):974–989. doi: 10.1016/j.kint.2022.08.012. [DOI] [PubMed] [Google Scholar]

4.Hsu, C. Y. et al. The risk of acute renal failure in patients with chronic kidney disease. Kidney Int. 74, 101–107 (2008).

ArticleCASPubMedPubMed CentralGoogle Scholar

5.Coca, S. G., Singanamala, S. & Parikh, C. R. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int. 81, 442–448 (2012).

ArticlePubMedGoogle Scholar

6.GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 395, 709–733 (2020).

ArticleGoogle Scholar

7.Jager, K. J. et al. A single number for advocacy and communication-worldwide more than 850 million individuals have kidney diseases. Nephrol. Dial. Transplant. 34, 1803–1805 (2019).

ArticlePubMedGoogle Scholar

8.Gummidi, B. et al. A systematic study of the prevalence and risk factors of CKD in Uddanam, India. Kidney Int. Rep. 5, 2246–2255 (2020).

ArticlePubMedPubMed CentralGoogle Scholar0

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